meta分析

SNPmeta2-检索式

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第1章:亚甲基四氢叶酸还原酶(MTHFR)多态性与非酒精性脂肪性肝病(NAFLD)之间的关联风险:meta分析

Man-Yi Sun, Li Zhang, Song-Li Shi, Jing-Na Lin

Published: April 29, 2016http://dx.doi.org/10.1371/journal.pone.0154337

http://dx.doi.org/10.1371/journal.pone.0154337

全文地址:http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0154337

 

Methods

Searching strategy

A computerized literature search was performed from the electronic databases, including PubMed, Excerpta Medica Database (EMBASE), Cochrane Central Register of Controlled Trials (CENTRAL), Web of Science (WOS), China National Knowledge Infrastructure (CNKI)/WANFANG, Scopus and EBSCOhost in April 1st, 2016. There was no language or region restriction. The combinations of following keywords were used: “Methylenetetrahydrofolate Reductase (NADPH)” or “Methylene-THF Reductase (NADPH)” or “MTHFR” or “Methylenetetra hydrofolate Reductase”; “Non-alcoholic Fatty Liver Disease” or “NAFLD” or “Fatty Liver, Nonalcoholic” or “Livers, Nonalcoholic Fatty” or “Nonalcoholic Fatty Livers” or “Nonalcoholic Steatohepatitis” or “Nonalcoholic Steatohepatitides” or “Steatohepatitides, Nonalcoholic” or “Steatohepatitis, Nonalcoholic”; “Polymorphism, Genetic” or “Genetic Polymorphisms” or “Genetic Polymorphism” or “Polymorphism (Genetics)” or “Polymorphisms, Genetic”. The full details of databases searching terms were also provided

检索策略(正文)

从电子数据库,包括PubMed,EMBASE,Cochrane试验中心(CENTRAL),Web of Science(WOS),CNKI/ WANFANG,Scopus和EBSCOhost在2016年4月1日。没有语言或地区的限制。使用以下关键词的组合:“亚甲基四氢叶酸还原酶(NADPH)”或“亚乙基-THF还原酶(NADPH)”或“MTHFR”或“亚甲基四氢叶酸还原酶”; “非酒精性脂肪性肝病”或“NAFLD”或“脂肪肝,非酒精性”或“肝脏,非酒精性脂肪肝”或“非酒精性脂肪肝”或“非酒精性脂肪性肝炎”或“非酒精性脂肪肝”或“非酒精性脂肪肝,非酒精性脂肪肝”脂肪性肝炎,不含酒精”;“多态性遗传”或“遗传多态性”或“遗传多态性”或“多态性(遗传学)”或“多态性,遗传”)

 

#第二部分  检索式###########

Databases searching terms

(updated to April 1st, 2016)

(1)    Pubmed Database (n=10)

#1:((((((Methylenetetrahydrofolate Reductase (NADPH2)) OR Methylenetetrahydrofolate Reductase (NADPH)) OR Methylene-THF Reductase (NADPH)) OR Methylenetetrahydrofolate Reductase) OR 5,10-Methylenetetrahydrofolate Reductase (NADPH)) OR Methylene Tetrahydrofolate Reductase) OR Tetrahydrofolate Reductase, Methylene -----5036

#2:(((((((((((Non-alcoholic Fatty Liver Disease) OR Non alcoholic Fatty Liver Disease) OR NAFLD) OR Nonalcoholic Fatty Liver Disease) OR Fatty Liver, Nonalcoholic) OR Fatty Livers, Nonalcoholic) OR Nonalcoholic Fatty Liver) OR Nonalcoholic Fatty Livers) OR Nonalcoholic Steatohepatitis) OR Nonalcoholic Steatohepatitides) OR Steatohepatitides, Nonalcoholic) OR Steatohepatitis, Nonalcoholic----- 12742

#1 and #2: (((((((((((((Non-alcoholic Fatty Liver Disease) OR Non alcoholic Fatty Liver Disease) OR NAFLD) OR Nonalcoholic Fatty Liver Disease) OR Fatty Liver, Nonalcoholic) OR Fatty Livers, Nonalcoholic) OR Nonalcoholic Fatty Liver) OR Nonalcoholic Fatty Livers) OR Nonalcoholic Steatohepatitis) OR Nonalcoholic Steatohepatitides) OR Steatohepatitides, Nonalcoholic) OR Steatohepatitis, Nonalcoholic)) AND (((((((Methylenetetrahydrofolate Reductase (NADPH2)) OR Methylenetetrahydrofolate Reductase (NADPH)) OR Methylene-THF Reductase (NADPH)) OR Methylenetetrahydrofolate Reductase) OR 5,10-Methylenetetrahydrofolate Reductase (NADPH)) OR Methylene Tetrahydrofolate Reductase) OR Tetrahydrofolate Reductase, Methylene) -----10

(2)    EMBASE Database (n=29)

#1 ('Methylenetetrahydrofolate Reductase' OR 'MTHFR') AND ('nonalcoholic fatty liver' OR 'NAFLD' OR 'Nonalcoholic Fatty Liver Disease' OR 'Nonalcoholic Steatohepatitis' OR 'Nonalcoholic Steatohepatitides') AND ('polymorphism' OR 'Genetic Polymorphism' OR 'variants' OR 'variant' OR 'mutation' OR 'mutations' OR 'SNP' OR 'Single Nucleotide Polymorphism') -----32

#1 AND limit 1 to human-----29

(3)    Cochrane Central Register of Controlled Trials (CENTRAL) Database (n=0)

#1:  MeSH descriptor: [Methylenetetrahydrofolate Reductase (NADPH2)] explode all trees-----166

#2:  MeSH descriptor: [Polymorphism, Genetic] explode all trees-----3350

#3: MeSH descriptor: [Non-alcoholic Fatty Liver Disease] explode all trees-----134

#4:#1 and #2 and #3-----0

(4)     Web of Science (WOS) Database (n=24)

TS=((((((((((((((Non-alcoholic Fatty Liver Disease) OR Non alcoholic Fatty Liver Disease) OR NAFLD) OR Nonalcoholic Fatty Liver Disease) OR Fatty Liver, Nonalcoholic) OR Fatty Livers, Nonalcoholic) OR Nonalcoholic Fatty Liver) OR Nonalcoholic Fatty Livers) OR Nonalcoholic Steatohepatitis) OR Nonalcoholic Steatohepatitides) OR Steatohepatitides, Nonalcoholic) OR Steatohepatitis, Nonalcoholic)) AND (((((((Methylenetetrahydrofolate Reductase (NADPH2)) OR Methylenetetrahydrofolate Reductase (NADPH)) OR Methylene-THF Reductase (NADPH)) OR Methylenetetrahydrofolate Reductase) OR 5,10-Methylenetetrahydrofolate Reductase (NADPH)) OR Methylene Tetrahydrofolate Reductase) OR Tetrahydrofolate Reductase, Methylene)) -----24

(5)    CNKI / WANFANG Database (n=3)

CNKI

主题: MTHFR 基因多态性 非酒精性脂肪肝-----1

WANFANG

mthfr * 基因多态性 * 非酒精性脂肪肝 * Date:-2016-----2

(6)    Scopus Database (n=144)

('Methylenetetrahydrofolate Reductase' OR 'MTHFR') AND ('nonalcoholic fatty liver disease' OR 'NAFLD') AND 'polymorphisms'-----144

(7)    EBSCOhost Databases (n=11)

('Methylenetetrahydrofolate Reductase' OR 'MTHFR') AND ('nonalcoholic fatty liver disease' OR 'NAFLD') AND 'polymorphisms'-----11

 

###猴哥摘要解析:

1.检索数据库:PubMed,EMBASE,CENTRAL,WOS,Scopus和EBSCOhost(2016年4月1日更新)的在线数据库进行合格的病例对照研究

2.检索需提供检索时间,检索条目,和检索结果

3.检索式需要有可重复性和可行性

4.本文提供了一个非常好的模板

5.应用了主题词、下位词、自由词等检索方式,检索数据较全,检索式需要我们自己反复修订。

拓展知识:

SNPmeta

SNPMETA1

SNPMETA2_检索式

SNPMETA3_索要原始文献+数据提取

 

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网状meta分析必备技能2_R软件gemtc包

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网状Meta分析必备技能4_Gemtc实现生存分析

网状meta分析必备技能5_HR风险比

网状meta分析必备技能6_R+Rstudio运用meta包做简单meta分析

网状meta分析必备技能7_使用R、GeMTC和STATA软件实现连续变量的网状Meta分析

 

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NMA(网状meta分析)stata简易教程(3)贡献图

NMA(网状meta分析)stata简易教程(4)漏斗图的制作

NMA(网状meta分析)stata简易教程(5)排序图的制作

 

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诊断性meta分析简单实现(5)_结果的展示和解读

 

其他

meta分析统计方法-随机对照试验的风险评估rob

生物标记物(基因)联合诊断模型的stata实现ROC(AUC)

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  1. liu18252586797
    liu18252586797发布于: 

    可以教教怎么写检索式吗

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